Oral Characteristics in Individuals With PTEN Hamartoma Tumour Syndrome.
AI interpretation is pending for this paper.
Open original publication →What the AI sees
Not AI summarized yet.
Research significance
Pending deeper interpretation.
Source abstract
AIM: To describe the oral characteristics and evaluate the oral health status of patients with PTEN hamartoma tumour syndrome (PHTS). MATERIALS AND METHODS: This descriptive cross-sectional study enrolled participants diagnosed with PHTS at Haukeland University Hospital, Bergen, Norway. A comprehensive oral investigation was performed, including clinical dental and periodontal examination, assessments of gingival overgrowth and palate architecture, intraoral radiographs, orthopantomogram and intraoral optical scanning. RESULTS: Twenty PHTS patients (13 females), with a median age of 45 years, participated in the study. A median of 25.5 teeth were present, and a DMFT score of 17 and DMFS score of 58 were recorded. Eleven patients (55%) were diagnosed with periodontitis, with seven classified as stage II, grade B, and four as stage IV, grade C. Nineteen patients (95%) had gingival overgrowth; the median clinical and photographic gingival overgrowth score was 2.0 and 40%, respectively, with 45% of the patients requiring treatment for the condition. Mucosal lesions were a universal finding. Palate height index was 52.0. Eight patients had 13 cancer diagnoses in total. CONCLUSION: PHTS patients face significant oral health challenges, including compromised dental and periodontal health, prevalent gingival overgrowth, mucosal lesions and a high-arched palate. The findings highlight oral features that may facilitate early recognition of PHTS and reinforce the importance of integrating oral health care into patient management.