Adult-Onset Eccrine Angiomatous Hamartoma Associated with Lower Extremity Venous Insufficiency: A Case Report.
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INTRODUCTION: Eccrine angiomatous hamartoma (EAH) is a benign tumor characterized by the proliferation of eccrine glands and vascular structures. It can be congenital or appear during childhood, with rare cases arising in adults. EAH typically presents as a solitary purplish plaque or nodule but a multifocal presentation in a blaschkoid or segmental distribution has been described. CASE PRESENTATION: We report the case of an extensive EAH following the territory of the superficial veins of the lower limbs, arising in an adult diagnosed with venous insufficiency at a young age and that worsened after saphenectomy. CONCLUSION: The histopathological and ultrasonographic characteristics suggest that this case may represent a new instance of EAH associated with arteriovenous malformation. We hypothesize that there might be common molecular pathways linking both conditions and that, in predisposed patients, saphenectomy can exacerbate EAH.