Diagnostic and therapeutic challenges of locally advanced colon cancer complicated with acute lymphoblastic leukemia: A case report.
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Colorectal cancer (CRC) is the second most common malignant tumor in China, characterized by a steadily increasing annual incidence. Acute lymphoblastic leukemia (ALL) is a malignant clonal disorder originating from lymphoid progenitor cells that predominantly affects children and adolescents. Its incidence is relatively lower in adults than in children, however they typically experience poorer prognoses. Although CRC and ALL each have distinct pathological and epidemiological profiles, their coexistence as synchronous or metachronous double primary malignancies in the same patient is rare and their treatment strategies differ. The current study presents a case of locally advanced colon cancer concurrent with ALL, in which the patient underwent radical colon cancer surgery after achieving complete remission of ALL through induction chemotherapy.