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RESEARCH PAPER ANALYSIS

Probiotic supplement for the treatment of polycystic ovarian syndrome.

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PMID39719172
JournalPharmacology & therapeutics
Publication Date2024-12-22
Ingested2026-08-02 12:03 AM
EXECUTIVE SUMMARY

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ABSTRACT

Source abstract

Polycystic Ovarian Syndrome is one of the major prevalent causes of infertility reported worldwide nearly 6-26 %, especially in girls hitting puberty and women at their childbearing age. The main clinical manifestations include irregular menstrual cycle, small cysts on one or both ovaries, chronic oligo-anovulation, and hirsutism. The etiological criteria are very complex and related to many factors like obesity, insulin sensitivity, inflammation, hyperandrogenism, diabetes mellitus type II, cardiovascular diseases, and dysbiosis of gut microbiota. The given review focuses on managing PCOS through probiotics by analyzing the effects on the symptoms of the disease. The probiotics effective in treating PCOS belong to Bifidobacterium, Lactobacilli, Clostridium, Enterococcus, and other Lactic acid bacteria. Its significance in PCOS is mainly due to the antagonizing of the growth of pathogenic microorganisms, increasing intestinal mucus layer production, reducing intestinal permeability, and modulating the gastrointestinal immune system. Also, their interaction with certain hormones such as insulin, androgen, and estrogen through short-chain fatty acids influences fertility. More research is necessary to validate these results. Probiotic supplements could be a viable option for treating PCOS in adults.

SUPPORTING PAPER SET

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Cureus 47.5 6 Self-reported oral health-related quality of life among pediatric oncology patients: a cross-sectional study at Kenyatta National Hospital, Kenya. Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD 61.4 7 Case Report: Intracranial germ cell tumors in girls presenting with peripheral precocious puberty and arginine vasopressin deficiency. Frontiers in endocrinology 56.3 8 Rectal colonization with multidrug-resistant organisms in adult acute leukemia patients undergoing allogeneic hematopoietic stem cell transplantation: a retrospective, longitudinal, single-center study. Frontiers in cellular and infection microbiology 72.76 9 Artificial intelligence-enabled nursing surveillance for pediatric cancer immunotherapy: integrating biomarkers, patient-reported outcomes, and long-term toxicity management. Frontiers in medicine 74.0 10 Double heterozygous pathogenic germline APC and MSH2 variants in a 16-year-old female diagnosed with colorectal cancer. Familial cancer 56.0 11 Ferroptotic stress selectively enhances ACSL4 translation during global translational repression in glioblastoma models. Molecular biology reports 58.2 12 Cured but What's Next? Rethinking Survivorship Care for Adolescent and Young Adult Testicular Cancer Survivors. European urology oncology 79.0 13 Dietary patterns and cardiovascular risk in adult survivors of childhood cancer: findings from the SCCSS-Nutrition Study. Journal of cancer survivorship : research and practice 56.0 14 SJIP38: A single-tube 38-parameter spectral immunophenotyping panel for the lineage classification of pediatric leukemias. Cytometry. Part B, Clinical cytometry 57.2 15 Divergent Trends in Head and Neck Cancer Burden in China (1990-2021). Asia-Pacific journal of clinical oncology 61.6 16 Low albumin levels precede mucormycosis in pediatric cancer patients. Medical mycology 63.9 17 Variance decomposition of probabilistic health risk of potentially toxic metals at two Nigerian artisanal mining fields. Environmental geochemistry and health 57.5 18 High school students' perspectives on childhood cancer: A metaphorical analysis. Journal of pediatric nursing 57.2 19 Antibody-drug conjugates in the treatment of Leukemia: a constraint-satisfaction heuristic analysis of global clinical trials. Translational oncology 68.56 20 Determinants of Systemic Anticancer Treatment and Continuous Intravenous Opioid and/or Benzodiazepine Use at End of life: A Real-World Analysis of Demographic and Clinical Factors in Advanced Cancer Patients. Clinical medicine (London, England) 79.04 21 Comment on "Understanding the Immune Response Changes to Clinical Interventions for Epstein-Barr Virus Infection Prior to Lymphoma Development in Children After Organ Transplants (UNEARTH)". Pediatric transplantation 51.82 22 Paediatric chronic hepatitis C and the global elimination gap: burden and trends from 1990 to 2023 in the Global Burden of Disease Study 2023. EClinicalMedicine 59.9 23 Pediatric and Adolescent Cancers Among American Indian and Alaska Native Peoples. Pediatrics 64.7 24 Exploratory Profiling of ABC-Family Genes Identifies a Candidate Score in Pediatric Neuroblastoma. Cancer genomics & proteomics 63.9 25 Human health risk assessment of selected trace elements in water-soil-vegetables system in Lephalale, Limpopo province, South Africa. Toxicology reports 57.5 26 Orofacial Cleft Characteristics in Van der Woude Syndrome: A Retrospective Study in Japan. Congenital anomalies 61.5 27 Spectrum of oral and maxillofacial pathologies in pediatric patients: A decade-long institutional study in South Kerala. Indian journal of pathology & microbiology 49.0 28 A clinicopathological study of gonadal tumors in differences in sex development: Experience from a tertiary care centre. Indian journal of pathology & microbiology 58.4 29 Suprasellar neuroblastoma in an adult: Challenges in neuropathological diagnosis. Indian journal of pathology & microbiology 45.5 30 Hypothalamic hamartoma in a child with Pallister-Hall syndrome: Report of a rare lesion successfully managed with multidisciplinary approach. Indian journal of pathology & microbiology 56.0 31 Orbital neuromuscular choristoma (benign triton tumor) presenting as a painful blind eye: A rare case report. Indian journal of pathology & microbiology 45.5 32 Physical activity and health-related quality of life in women with polycystic ovary syndrome attending fertility clinics in Sri Lanka: a cross-sectional study. BMC women's health 64.0
PATIENT-FRIENDLY SUMMARY

Probiotic supplement for the treatment of polycystic ovarian syndrome.

For education only—not personal medical advice.

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