Clinical Trials for Children and Adolescents With Cancer in Latin America.
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The improvement of childhood cancer outcomes has relied on clinical trials. The WHO's International Clinical Trials Registry Platform was searched for interventional clinical trials for children and adolescents with cancer in Latin America. Forty-seven trials were identified. Institutions were the primary sponsors for 38 (88.8%) trials, and 31 (65.9%) were conducted at a single site. Supportive care interventions (26, 55.3%) were more common than cancer-directed treatment trials. Thirteen (27.6%) trials had published results. Few trials were registered in Latin America. Strengthening research infrastructure and fostering collaborations are essential for equity in pediatric cancer research in the region.