[Cancer Genome Profiling of Pediatric Brain Tumor].
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Precision medicine in pediatric brain tumors aims to transcend traditional organ-based therapy by customizing treatment according to each patient's tumor molecular and genomic profiles. By leveraging comprehensive genomic profiling and expert panel reviews, actionable mutations may direct the use of targeted therapies or immunotherapies. In July 2025, three oncology societies in Japan released a joint briefing report outlining 12 reform proposals to optimize the cancer gene panel testing system. Included among these are timing restrictions on testing, loosening the expert panel criteria. These reforms are designed to enhance test utility, improve patient access, and ultimately improve survival outcomes of pediatric patients with brain tumors.