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RESEARCH PAPER ANALYSIS

EndoCompass Project: Research Roadmap for Thyroid Endocrinology.

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PMID41325413
JournalHormone research in paediatrics
Publication Date2025-12-01
Ingested2026-08-02 12:03 AM
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ABSTRACT

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BACKGROUND: Endocrine science remains underrepresented in European Union research programs despite the fundamental role of hormone health in human well-being. Analysis of the CORDIS database reveals a persistent gap between the societal impact of endocrine disorders and their research prioritization. At national funding level, endocrine societies report limited or little attention of national research funding toward endocrinology. The EndoCompass project - a joint initiative between the European Society of Endocrinology and the European Society of Paediatric Endocrinology, aimed to identify and promote strategic research priorities in endocrine science to address critical hormone-related health challenges. METHODS: Research priorities were established through comprehensive analysis of the EU CORDIS database covering the Horizon 2020 framework period (2014-2020). Expert consultation in thyroid endocrinology was conducted to identify key research priorities, followed by broader stakeholder engagement including society members and patient advocacy groups. RESULTS: For thyroid disorders, research priorities encompass neoplastic and nonneoplastic conditions, focusing on disease mechanisms, improved diagnostics and treatments, and the impact of environmental and metabolic factors. Key areas include personalized medicine approaches, artificial intelligence applications, and the establishment of pan-European registries to advance understanding of rare thyroid conditions. CONCLUSIONS: The thyroid component of the EndoCompass project provides an evidence-based roadmap for strategic research investment. This framework identifies crucial investigation areas into thyroid disease pathophysiology, prevention, and treatment strategies, ultimately aimed at reducing the burden of thyroid disorders on individuals and society. The findings support the broader EndoCompass objective of aligning research funding with areas of highest potential impact in endocrine health.

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Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 69.64 19 Thyroid Differentiation Score as a Molecular Bridge Between Genotype, Tumor Biology, and Radioiodine Theranostics in Thyroid Cancer. Endocrine-related cancer 64.7 20 [Development and validation of a prediction model for postoperative recurrence risk of ovarian endometriotic cysts based on preoperative imaging and clinical biomarkers]. Zhonghua yi xue za zhi 71.75 21 Lactation Management in Patients With Cancer: An Evidence-Based Framework for Surgical Practice. The American surgeon 71.0 22 Evidence-Based Recommendations for School Integration Programs Following Cancer: A Systematic Review. Journal of pediatric hematology/oncology nursing 70.0 23 Discharge Planning in Children With Cancer: Components, Strategies, and Outcomes-A Scoping Review (2021-2025). Journal of pediatric hematology/oncology nursing 58.0 24 Intervention to Support Families of Survivors of Pediatric Brain Tumor: A Scoping Review. Journal of pediatric hematology/oncology nursing 72.7 25 The role of allogeneic hematopoietic stem cell transplantation in adults with mature T-cell lymphomas. The Cochrane database of systematic reviews 88.6 26 Relative frequency of non-Wilms renal tumours in children: an institutional experience from a national tertiary referral centre in Malaysia. Pediatric surgery international 63.4 27 Childhood Cancer Risk After Assisted Reproductive Technology. JAMA 50.0 28 Long-Term Outcomes and Biomarker Correlates of a Multi-Institutional Phase II Study of Hypofractionated Proton Beam Therapy for Unresectable Primary Liver Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 83.39 29 The Burden of Early-Onset Gastric Cancer From 1990 to 2021: A Systematic Analysis for the Global Burden of Disease Study 2021. Journal of clinical gastroenterology 58.0 30 Decomposing the decline in life expectancy at birth by cause of death during the COVID-19 pandemic in Canada. Health reports 38.5 31 Integrating Surgery and Immunotherapy in the Treatment of Childhood Orbital Melanoma: A Case Report and the Literature Review. Ophthalmic plastic and reconstructive surgery 62.56 32 Co-occurrence of retinoblastoma and oculocutaneous albinism in a Mexican patient: a case report. Ophthalmic genetics 51.9
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EndoCompass Project: Research Roadmap for Thyroid Endocrinology.

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