Experimental Treatment of Measles Encephalitis With Inosine Pranobex and Remdesivir in a Child With Lymphocytic Leukemia.
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Measles encephalitis results in devastating epilepsia partialis and/or mortality in the majority of children treated with intense chemotherapy for hematolymphoid malignancies. Although many agents have been studied in the treatment of Measles encephalitis with variable results, there are no effective strategies to mitigate the significant morbidity associated with measles encephalitis till date and treatment has remained largely supportive. In this report, a novel combination of antivirals have been shown to abrogate the morbid sequelae of Measles encephalitis with eventual complete recovery in a child with B-acute lymphoblastic leukemia.