Management of Pediatric and Adolescent Rhabdomyosarcoma of the Chest Wall: An Expert Consensus Opinion From the International Soft Tissue Sarcoma Consortium (INSTRuCT).
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The International Soft-Tissue Sarcoma Consortium (INSTRuCT) was established as a global partnership among various pediatric soft tissue sarcoma groups, including the Children's Oncology Group (COG), European Pediatric Soft Tissue Sarcoma Group (EpSSG), and Cooperative Weichteilsarkom Studiengruppe (CWS). One of INSTRuCT's primary objectives is to create consensus expert opinions for optimal clinical treatment. This consensus document provides evidence-based treatment recommendations for patients with rhabdomyosarcoma of the chest wall, including guidelines for staging, biopsy methods, local control strategies, radiation therapy, surgery timing, lymph node evaluation, reconstructive techniques, and long-term follow-up.