Primary Intrarenal Yolk Sac Tumor in a Child: A Case Report with Summary of Prior Published Cases.
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BACKGROUND: Renal tumors are common primary tumors in children with Wilms tumor being the most prevalent one. Others include clear cell sarcoma kidney, congenital mesoblastic nephroma and rhabdoid tumors. Extragonadal germ cell tumors especially primary intrarenal yolk sac tumor (YST) is extremely uncommon. Only 6 cases of primary intrarenal YST have been reported so far. CASE REPORT: A 2-year-old boy presented with a left sided abdominal mass. Imaging studies were consistent with Wilms tumor. He received chemotherapy followed by nephrectomy. Histopathological examination revealed a primary intrarenal yolk sac tumor. CONCLUSION: This case report emphasizes the need to include germ cell tumors, particularly YSTs, in the differential diagnosis of pediatric renal tumors.