Giant mesenteric cysts: Clinical insights and diagnostic challenges.
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INTRODUCTION AND SIGNIFICANCE: Giant mesenteric cysts are rare and their clinical presentation varies depending on their location and size and therefore varies widely in clinical manifestations. Many theories have attempted to explain the occurrence of these tumors but no precise cause has been found. However, surgical excision is the gold standard in the treatment of these tumors and there is no need for adjuvant radiotherapy or chemotherapy. CASE PRESENTATION: We present three cases of male children with giant mesenteric cysts in different abdominal regions with different clinical manifestations, all of which had no abdominal pain but abdominal distension as the main complaint. Radiological investigations confirmed the presence of intra-abdominal cysts without precise localization, and surgical intervention was successful and these tumors were completely removed. CLINICAL DISCUSSION: While these conditions are rare and not frequently seen by surgeons, they should be considered as a differential diagnosis for intra-abdominal cysts, as this is important for the outcome of correct treatment. CONCLUSION: These tumors are often diagnosed during surgery and complete surgical excision is essential and the diagnosis is confirmed by histological analysis. The clinical findings of this study suggest that environmental factors are a possible cause of the development of these tumors, which requires further study to understand the pathophysiology of these tumors.