Impact of Amputation Level and Oncologic Prognosis on Activities of Daily Living in Patients with Lower Limb Amputation for Musculoskeletal Malignancies.
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Activities of daily living (ADLs) with phantom limb pain (PLP) and prosthesis use in patients who underwent lower limb amputation for musculoskeletal malignancies has been reported just by a few researchers. This study aimed to investigate the influence of PLP and prosthesis use on ADLs after lower limb amputation for musculoskeletal malignancies. We conducted a retrospective study on 19 patients (10 males and 9 females) who underwent lower limb amputation for musculoskeletal malignancies between 2003 and 2011 and were followed up until 2021. The mean age was 60.4 (range, 10-85) years. We investigated PLP, prosthesis use, and ADLs after lower limb amputation; we used the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) to assess ADLs. PLP was present in 16 patients (84%), and 4 of 5 survivors (80%) were medication-free at the final follow-up. Prostheses were prescribed in 16 patients (84%), and 11 patients (69%) continued to use the prosthesis after discharge. In a multiple linear regression analysis of ADLs at discharge for the 15 patients with confirmed survival or death, excluding the four patients whose outcome was unknown at the last follow-up, lower-level amputation and good oncologic prognosis were positive independent factors, while age was the only negative independent factor. PLP and prosthesis use did not influence ADLs.