A grade PMID 42321916
View analysis →Finding therapies hidden in 39,079 pediatric cancer papers.
Neurocompute scores pediatric oncology literature, surfaces overlooked therapeutic signals, and turns fragmented childhood cancer research into a living discovery terminal.
Ranked Discovery Journal Articles
A grade PMID 42690647
View analysis →A grade PMID 42372741
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All ranked pediatric cancer papers
In phenomenological interviews with 14 mothers of children with acute lymphoblastic leukemia in Turkey, the study identified substantial emotional distress, social and caregiving pressures, reliance on strategies such as suppression, catastrophizing, and rumination, and difficulties recognizing, expressing, and regulating emotions.
The evidence identifies potentially modifiable emotion-regulation difficulties in mothers; it supports the inference that nurse-led psychoeducation emphasizing adaptive regulation strategies might improve caregiver psychological well-being, but no intervention or clinical benefit was tested.
In 234 paired pre/post surveys at one medical school, an HPV infographic was associated with improved student knowledge and greater willingness to encourage family vaccination, but not increased intention to recommend vaccination to future patients.
Evidence: the infographic improved measured HPV knowledge and one self-reported vaccination-promotion attitude. Inference: incorporating similar education into medical curricula could eventually increase HPV vaccine counseling or uptake and thereby help prevent HPV-associated cancers, but this study did not measure counseling behavior, vaccination rates, cancer incidence, or pediatric outcomes.
This single-center descriptive qualitative study used interviews with 12 Turkish fathers of children receiving cancer treatment to identify themes concerning treatment experiences, life changes, coping, and support needs, with implications for more inclusive nursing care.
The study provides evidence of paternal experiences and perceived needs; it supports, but does not test, the hypothesis that culturally sensitive, father-focused nursing interventions could improve paternal involvement, coping, and family-centered supportive care during pediatric cancer treatment.
In a cross-sectional survey of AYA cancer survivors treated in West Virginia, qualitative responses from 22 participants identified information gaps, social isolation, treatment and pain concerns, financial and logistical burdens, and survivorship re-entry challenges.
The study provides evidence of perceived supportive-care gaps, particularly in a rural setting; it is reasonable but untested to hypothesize that tailored navigation, mental-health, fertility, peer-support, transportation, and survivorship services could improve patient experience or outcomes.
This cross-sectional web survey of 1,482 adult Saudi residents found low knowledge and moderate attitudes and practices concerning H. pylori-related ulcers and gastric cancer, including misconceptions about treatment, self-medication, and premature antibiotic discontinuation.
The evidence identifies potentially modifiable public knowledge and medication-use gaps; as an inference, targeted education or antimicrobial-adherence interventions might improve H. pylori management and possibly reduce downstream ulcer and gastric-cancer risk, but no intervention or clinical outcome was tested.
This case report describes an 8-year-old boy with anti-GQ1b antibody-positive overlapping Bickerstaff brainstem encephalitis, Guillain–Barré syndrome, and acute transverse myelitis who showed neurological and radiological improvement after intravenous immunoglobulin and corticosteroid pulse therapy.
The reported improvement provides case-level evidence that combined immunotherapy may be active in this rare anti-GQ1b overlap syndrome; whether treatment caused the improvement, is superior to either therapy alone, or has relevance to pediatric oncology remains untested.
This pictorial review summarizes typical and atypical MRI findings of the four WHO CNS5 paediatric-type diffuse low-grade glioma entities and emphasizes their distinction from high-grade gliomas, non-glial tumours, and adult diffuse gliomas.
The record supports imaging-informed diagnosis, surgical planning, and monitoring rather than a therapy; it can only be inferred that more accurate recognition of molecularly defined pDLGG subtypes—particularly MAPK pathway-altered tumours—might improve treatment selection or reduce inappropriate management, but no therapeutic intervention or outcome evidence is reported.
This review summarizes current surgical and overall management principles for pediatric and adolescent extracranial germ cell tumors, emphasizing site-specific surgery for treatment and staging while preserving organ function and future fertility.
The supplied record supports the clinical principle that appropriately tailored surgery is central to extracranial germ cell tumor management; it can be inferred, but is not directly demonstrated here, that optimizing site-specific surgical approaches may improve cure opportunities while limiting functional and fertility-related harm.
This single-center retrospective study of 16 children with fibrous hamartoma of infancy found universal initial imaging misdiagnosis and identified serpentine and fence-like ultrasonographic patterns that may aid recognition, while confirming that definitive diagnosis remains histopathologic.
The record provides diagnostic rather than therapeutic evidence; it supports the hypothesis that integrating age, clinical features, and characteristic ultrasound patterns with multimodal imaging could reduce preoperative misclassification and potentially improve surgical planning, but this inference requires prospective external validation.
This retrospective case series of 127 adolescents found that fibroadenomas predominated among females and pubertal gynecomastia among males, with some secondary gynecomastia linked to hypogonadism or medication use and 40 patients undergoing surgery.
The study provides descriptive evidence that comprehensive evaluation can identify potentially addressable secondary causes of adolescent gynecomastia; it is reasonable to infer that cause-directed management might avoid or better select surgical treatment, but comparative effectiveness, safety, and oncology-specific benefit were not tested.
Among 80 female childhood cancer survivors aged 16–40 years who had received gonadotoxic therapy and lacked prior fertility preservation or post-treatment REI referral, 7 agreed to referral, 1 attended a consultation, and none underwent fertility preservation.
The reported low progression from counseling to referral, consultation, and fertility preservation suggests—without testing—that barrier-informed navigation or other post-treatment engagement interventions could increase use of reproductive endocrinology and infertility services.
This retrospective review of 521 pediatric emergency-department epistaxis presentations found that cancer history, otolaryngology consultation, and bleeding severity were independently associated with longer length of stay, while other clinical factors predicted severity or recurrence.
The evidence supports cancer history as a predictor of longer emergency-department stay, but not as a predictor of bleeding severity, recurrence, or response to a particular intervention; it may therefore justify prospective evaluation of oncology-informed triage pathways, although any improvement in care or outcomes remains inferential.