A grade PMID 42321916
View analysis →Finding therapies hidden in 39,079 pediatric cancer papers.
Neurocompute scores pediatric oncology literature, surfaces overlooked therapeutic signals, and turns fragmented childhood cancer research into a living discovery terminal.
Ranked Discovery Journal Articles
A grade PMID 42690647
View analysis →A grade PMID 42372741
View analysis →A grade PMID 42216567
View analysis →A grade PMID 41916649
View analysis →A grade PMID 42382416
View analysis →A grade PMID 42150584
View analysis →B grade PMID 42748428
View analysis →A grade PMID 41756844
View analysis →A grade PMID 42765973
View analysis →A grade PMID 42362103
View analysis →A grade PMID 42101908
View analysis →Database feed
All ranked pediatric cancer papers
This erratum reports that Table 1 in a review and meta-analysis of house-dust-mite sublingual immunotherapy for allergic rhinoconjunctivitis was published with an error and provides a corrected study summary table.
The supplied record supports only a correction to evidence about sublingual allergen immunotherapy for allergic rhinoconjunctivitis; it provides no evidence for a pediatric-oncology therapeutic hypothesis, and any relevance to cancer treatment would be unsupported inference.
This 17-year single-center retrospective cohort of 817 adults undergoing 1,101 double-balloon enteroscopy procedures reports age-associated differences in indications, findings, interventions, and complications, with tumors and vascular lesions occurring more frequently among elderly patients.
Evidence: age was associated with distinct DBE indications and findings, and therapeutic procedures were more frequent in elderly adults. Inference: age-informed selection for DBE might improve diagnostic targeting and enable endoscopic treatment of selected small-bowel lesions, but the record provides no pediatric cohort, oncology-specific treatment analysis, or evidence of improved cancer outcomes.
In a single-centre retrospective cohort of 2,222 patients with primary pilonidal sinus disease, off-midline flap procedures—particularly Karydakis and Bascom cleft lift—were associated with lower long-term recurrence than lay-open treatment, while higher body mass index and smoking were associated with increased recurrence.
The reported associations support the hypothesis that off-midline flap techniques may reduce recurrence and postoperative infection in primary pilonidal sinus disease, but comparative prospective studies would be needed to establish causality; the supplied record provides no pediatric-cancer therapeutic hypothesis or oncology-specific evidence.
This systematic review synthesized 56 publications into the Skuba Classification, a 16-category, color-coded anatomic framework based on the dural attachment of skull base meningiomas.
The record supports a standardized anatomic classification, not a therapy; it may indirectly improve treatment planning, interdisciplinary communication, and outcome comparisons, but benefit to treatment selection or patient outcomes—particularly in children—remains an untested inference.
This single-center retrospective cohort describes substantial early tumor and imaging burden among 38 children and young adults with suspected schwannomatosis, predominantly NF2-related disease, with bilateral vestibular schwannomas in 30 of 31 diagnosed NF2-related cases.
The reported age-dependent manifestations and high tumor burden provide evidence that pediatric and young-adult NF2-related schwannomatosis may warrant structured surveillance; it is an untested inference that age- and phenotype-adapted MRI, visual, and hearing monitoring could enable earlier intervention or reduce morbidity.
This single-infant case report describes post-neurosurgical meningitis caused by ESBL-producing, virulence-associated Klebsiella pneumoniae ST37 after tumor resection and EVD placement, with CSF sterilization following meropenem and EVD removal but persistent neurological sequelae.
The case provides direct but very limited evidence that prompt active antimicrobial therapy plus removal of an infected ventricular device can achieve microbiological clearance; it supports the hypothesis—not established by this report—that resistance-informed empiric therapy and early source control may improve outcomes in similarly exposed infants.
In a single-centre retrospective series of 18 eyes from 14 pediatric patients with glaucoma, SIBS microshunt implantation was associated with lower intraocular pressure and medication use at 12 months, with qualified success of 55% and complications in 2 eyes.
The evidence supports the SIBS microshunt as a possible surgical alternative for selected pediatric glaucoma cases; any relevance to pediatric oncology is unsupported by this record because no cancer population, anticancer treatment, or oncology-specific outcome was studied.
An 18-neurologist German-Austrian panel developed consensus-based guidance for initiating, sequencing, and switching complement C5 and neonatal Fc receptor inhibitors in generalized myasthenia gravis, primarily in adults, with additional considerations for juvenile disease.
The record supports the clinical inference that structured selection and sequencing of C5 or FcRn inhibitors may improve individualized management of active generalized myasthenia gravis; it provides no evidence that these strategies benefit pediatric cancer patients or represent an oncology treatment approach.
This environmental risk-assessment study modeled arsenic exposure in mining-affected Polish allotment gardens and found substantially elevated modeled risks for children, with ingestion and dermal contact dominating and bioaccessibility adjustment increasing the estimated remediation goal.
The record provides evidence for exposure reduction and site remediation as potential cancer-prevention measures, particularly for children, but it does not test an oncology treatment; any claim that remediation would reduce actual cancer incidence remains an inference from modeled risk.
In a retrospective cohort of 322 adults with newly diagnosed nasopharyngeal carcinoma, DeepSeek-V3 and ChatGPT-4o had moderate agreement with clinicians for overall staging but only slight agreement for preferred treatment recommendations.
The evidence indicates that these generative AI tools are not reliable substitutes for clinician treatment selection; as an inference requiring prospective validation, their stronger agreement for M staging could support development of narrowly scoped decision-support tools rather than autonomous oncology recommendations.
This case report describes a 7-year-old girl with an intramedullary conus lesion mimicking a tumor that was resected and identified histologically as Schistosoma haematobium granulomatous disease, followed by praziquantel, steroids, pain resolution, and partial-to-substantial motor recovery.
The reported case supports considering spinal schistosomiasis in the differential diagnosis of pediatric conus masses; it is reasonable—but unproven from this single multimodally treated case—to hypothesize that earlier recognition and targeted antiparasitic therapy could improve neurologic outcomes or alter the need for surgery in selected patients.
This review summarizes the clinicopathologic features, SMARCB1 loss, diagnosis, pathogenesis, and management of epithelioid sarcoma, emphasizing surgery for localized disease and the limited systemic options for advanced disease after tazemetostat withdrawal.
The record supports frequent SMARCB1 protein loss and homozygous deletion as disease-associated features; it is reasonable—but inferential from this review alone—to prioritize SMARCB1-linked vulnerabilities and alternative systemic strategies for unresectable or metastatic epithelioid sarcoma.