Targeting the BDNF/TrkB/CREB pathway: emerging strategies for neuroprotection in Parkinson's disease.
A review proposing modulation of the BDNF/TrkB/CREB neurotrophic signaling axis as a neuroprotective strategy in Parkinson’s disease, covering therapeutic approaches such as BDNF delivery, TrkB agonists, gene therapy and lifestyle interventions.
What the AI sees
A review proposing modulation of the BDNF/TrkB/CREB neurotrophic signaling axis as a neuroprotective strategy in Parkinson’s disease, covering therapeutic approaches such as BDNF delivery, TrkB agonists, gene therapy and lifestyle interventions.
Research significance
Targeting BDNF/TrkB/CREB is mechanistically relevant and offers multiple translational avenues to protect dopaminergic neurons, but the missing abstract and likely review nature limit immediate experimental or clinical actionability.
Source abstract
No abstract available.